Remodeling the Proteostasis Network to Rescue Glucocerebrosidase Variants by Inhibiting ER-Associated Degradation and Enhancing ER Folding

Open Access

Peer-reviewed

Research Article

Fan Wang,

Affiliation Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas, United States of America
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Laura Segatori

* E-mail: segatori@rice.edu

Affiliations Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas, United States of America, Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America, Department of Bioengineering, Rice University, Houston, Texas, United States of America
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Apoptosis
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Fibroblasts
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Lysosomes
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Protein folding
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Gene expression
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Homeostasis
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Small interfering RNA
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Cell binding
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