High Fat Diet Feeding Exaggerates Perfluorooctanoic Acid-Induced Liver Injury in Mice via Modulating Multiple Metabolic Pathways

Xiaobing Tan; Guoxiang Xie; Xiuhua Sun; Qiong Li; Wei Zhong; Peter Qiao; Xinguo Sun; Wei Jia; Zhanxiang Zhou

doi:10.1371/journal.pone.0061409

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Open Access

Peer-reviewed

Research Article

High Fat Diet Feeding Exaggerates Perfluorooctanoic Acid-Induced Liver Injury in Mice via Modulating Multiple Metabolic Pathways

Xiaobing Tan,

Affiliation Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯
Guoxiang Xie,

Affiliation Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯
Xiuhua Sun,

Affiliation Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯
Qiong Li,

Affiliation Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯
Wei Zhong,

Affiliation Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯
Peter Qiao,

Affiliation Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Xinguo Sun,

Affiliation Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯
Wei Jia ,

* E-mail: z_zhou@uncg.edu (ZZ); w_jia@uncg.edu (WJ)

Affiliations Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America, Department of Nutrition, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯
Zhanxiang Zhou

* E-mail: z_zhou@uncg.edu (ZZ); w_jia@uncg.edu (WJ)

Affiliations Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America, Department of Nutrition, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯

High Fat Diet Feeding Exaggerates Perfluorooctanoic Acid-Induced Liver Injury in Mice via Modulating Multiple Metabolic Pathways

Xiaobing Tan,
Guoxiang Xie,
Xiuhua Sun,
Qiong Li,
Wei Zhong,
Peter Qiao,
Xinguo Sun,
Wei Jia,
Zhanxiang Zhou

Published: April 23, 2013
https://doi.org/10.1371/journal.pone.0061409

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