Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1

Lin Lei; Sun Ying; Luo Baojun; Yang Yi; He Xiang; Su Wenli; Sun Zounan; Guo Deyin; Zhu Qingyu; Liu Jingmei; Chang Guohui

doi:10.1371/journal.pone.0061166

Loading metrics

Open Access

Peer-reviewed

Research Article

Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1

Lin Lei ,

Contributed equally to this work with: Lin Lei, Sun Ying

Affiliation State Key Laboratory of Pathogen and Biosecurity, Institute of Epidemiology and Microbiology, Academy of Millitary Medical Sciences, Beijing, China
⨯
Sun Ying ,

Contributed equally to this work with: Lin Lei, Sun Ying

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Luo Baojun,

Affiliation State Key Laboratory of Pathogen and Biosecurity, Institute of Epidemiology and Microbiology, Academy of Millitary Medical Sciences, Beijing, China
⨯
Yang Yi,

Affiliation Institute of Disease Prevention and Control, Academy of Military Medical Sciences, Beijing, China
⨯
He Xiang,

Affiliation Institute of Disease Prevention and Control, Academy of Military Medical Sciences, Beijing, China
⨯
Su Wenli,

Affiliation Institute of Disease Prevention and Control, Academy of Military Medical Sciences, Beijing, China
⨯
Sun Zounan,

Affiliation Institute of Disease Prevention and Control, Academy of Military Medical Sciences, Beijing, China
⨯
Guo Deyin,

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, China
⨯
Zhu Qingyu,

Affiliation State Key Laboratory of Pathogen and Biosecurity, Institute of Epidemiology and Microbiology, Academy of Millitary Medical Sciences, Beijing, China
⨯
Liu Jingmei ,

* E-mail: amay_l@163.com (LJ); changguohui999@yahoo.com.cn (CG)

Affiliation Institute of Disease Prevention and Control, Academy of Military Medical Sciences, Beijing, China
⨯
Chang Guohui

* E-mail: amay_l@163.com (LJ); changguohui999@yahoo.com.cn (CG)

Affiliations State Key Laboratory of Pathogen and Biosecurity, Institute of Epidemiology and Microbiology, Academy of Millitary Medical Sciences, Beijing, China, Institute of Disease Prevention and Control, Academy of Military Medical Sciences, Beijing, China
⨯

Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1

Lin Lei,
Sun Ying,
Luo Baojun,
Yang Yi,
He Xiang,
Su Wenli,
Sun Zounan,
Guo Deyin,
Zhu Qingyu,
Liu Jingmei

Published: April 8, 2013
https://doi.org/10.1371/journal.pone.0061166

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Coronaviruses
Is the Subject Area "Coronaviruses" applicable to this article?

Thanks for your feedback.
SARS coronavirus
Is the Subject Area "SARS coronavirus" applicable to this article?

Thanks for your feedback.
Viral gene expression
Is the Subject Area "Viral gene expression" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.
Vaccinia virus
Is the Subject Area "Vaccinia virus" applicable to this article?

Thanks for your feedback.
Hepatitis viruses
Is the Subject Area "Hepatitis viruses" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Mouse hepatitis virus
Is the Subject Area "Mouse hepatitis virus" applicable to this article?

Thanks for your feedback.