CD4+CD25−Nrp1+ T Cells Synergize with Rapamycin to Prevent Murine Cardiac Allorejection in Immunocompetent Recipients

Open Access

Peer-reviewed

Research Article

CD4⁺CD25⁻Nrp1⁺ T Cells Synergize with Rapamycin to Prevent Murine Cardiac Allorejection in Immunocompetent Recipients

Qing Yuan ,

Contributed equally to this work with: Qing Yuan, Shanjuan Hong

Affiliation Organ Transplant Center, Organ Transplant Institution of PLA, The 309th Hospital of PLA, Beijing, China
⨯
Shanjuan Hong ,

Contributed equally to this work with: Qing Yuan, Shanjuan Hong

Affiliation National Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai, China
⨯
Bingyi Shi,

Affiliation Organ Transplant Center, Organ Transplant Institution of PLA, The 309th Hospital of PLA, Beijing, China
⨯
Jesper Kers,

Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Zhouli Li,

Affiliation Organ Transplant Center, Organ Transplant Institution of PLA, The 309th Hospital of PLA, Beijing, China
⨯
Xiangke Pei,

Affiliation Organ Transplant Center, The 281th Hospital of PLA, Qinhuangdao, Hebei, China
⨯
Liang Xu,

Affiliation Organ Transplant Center, Organ Transplant Institution of PLA, The 309th Hospital of PLA, Beijing, China
⨯
Xing Wei,

Affiliation Organ Transplant Center, Organ Transplant Institution of PLA, The 309th Hospital of PLA, Beijing, China
⨯
Ming Cai

* E-mail: caiming309@gmail.com

Affiliation Organ Transplant Center, Organ Transplant Institution of PLA, The 309th Hospital of PLA, Beijing, China
⨯

T cells
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Regulatory T cells
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Cardiac transplantation
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Inflammation
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Cytokines
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Cytokine therapy
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Transplant rejection
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Immunosuppressives
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