Metabonomics Analysis of Plasma Reveals the Lactate to Cholesterol Ratio as an Independent Prognostic Factor of Short-Term Mortality in Acute Heart Failure

Franck Desmoulin; Michel Galinier; Charlotte Trouillet; Matthieu Berry; Clément Delmas; Annie Turkieh; Pierre Massabuau; Heinrich Taegtmeyer; Fatima Smih; Philippe Rouet

doi:10.1371/journal.pone.0060737

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Research Article

Metabonomics Analysis of Plasma Reveals the Lactate to Cholesterol Ratio as an Independent Prognostic Factor of Short-Term Mortality in Acute Heart Failure

Franck Desmoulin,

Affiliation INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France
⨯
Michel Galinier,

Affiliations INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France, CHU de Rangueil, Service de Cardiologie A, Toulouse, France
⨯
Charlotte Trouillet,

Affiliations INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France, CHU de Rangueil, Service de Cardiologie A, Toulouse, France
⨯
Matthieu Berry,

Affiliations INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France, CHU de Rangueil, Service de Cardiologie A, Toulouse, France
⨯
Clément Delmas,

Affiliations INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France, CHU de Rangueil, Service de Cardiologie A, Toulouse, France
⨯
Annie Turkieh,

Affiliation INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France
⨯
Pierre Massabuau,

Affiliations INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France, CHU de Rangueil, Service de Cardiologie A, Toulouse, France
⨯
Heinrich Taegtmeyer,

Affiliation Division of Cardiology, Department of Internal Medicine, The University of Texas Medical School at Houston, Houston, Texas, United States of America
⨯
Fatima Smih,

Affiliation INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France
⨯
Philippe Rouet

* E-mail: Philippe.rouet@inserm.fr

Affiliations INSERM I2MC, UMR 1048, Université UPS, Equipe «Obésité et insuffisance cardiaque: approches moléculaires et cliniques », Toulouse, France, CHU de Rangueil, Service de Cardiologie A, Toulouse, France
⨯

Metabonomics Analysis of Plasma Reveals the Lactate to Cholesterol Ratio as an Independent Prognostic Factor of Short-Term Mortality in Acute Heart Failure

Franck Desmoulin,
Michel Galinier,
Charlotte Trouillet,
Matthieu Berry,
Clément Delmas,
Annie Turkieh,
Pierre Massabuau,
Heinrich Taegtmeyer,
Fatima Smih,
Philippe Rouet

Published: April 3, 2013
https://doi.org/10.1371/journal.pone.0060737

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Cholesterol
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Blood plasma
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Heart failure
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NMR spectroscopy
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Inductively coupled plasma emission spectroscopy
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Death rates
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Metabolites
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