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Open Access

Peer-reviewed

Research Article

Knockdown of PPAR δ Gene Promotes the Growth of Colon Cancer and Reduces the Sensitivity to Bevacizumab in Nude Mice Model

Lie Yang ,

Contributed equally to this work with: Lie Yang, Jin Zhou

Affiliation Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
⨯
Jin Zhou ,

Contributed equally to this work with: Lie Yang, Jin Zhou

Affiliation Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
⨯
Qin Ma,

Affiliation Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
⨯
Cun Wang,

Affiliation Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
⨯
Keling Chen,

Affiliation Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
⨯
Wenjian Meng,

Affiliation Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
⨯
Yongyang Yu ,

* E-mail: zhou767@163.com (ZZ); yuyongyang@hotmail.com (YY)

Affiliation Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
⨯
Zongguang Zhou ,

* E-mail: zhou767@163.com (ZZ); yuyongyang@hotmail.com (YY)

Affiliation Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
⨯
Xiaofeng Sun

Affiliations Institute of Digestive Surgery and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China, Department of Oncology, Department of Clinical and Experiment Medicine, Linköping University, Linköping, Sweden
⨯

Knockdown of PPAR δ Gene Promotes the Growth of Colon Cancer and Reduces the Sensitivity to Bevacizumab in Nude Mice Model

Lie Yang,
Jin Zhou,
Qin Ma,
Cun Wang,
Keling Chen,
Wenjian Meng,
Yongyang Yu,
Zongguang Zhou,
Xiaofeng Sun

x

Published: April 8, 2013
https://doi.org/10.1371/journal.pone.0060715

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