Superiority of Trans-Oral over Trans-Nasal Sampling in Detecting Streptococcus pneumoniae Colonization in Adults

Krzysztof Trzciński; Debby Bogaert; Anne Wyllie; Mei Ling J. N. Chu; Arie van der Ende; Jacob P. Bruin; Germie van den Dobbelsteen; Reinier H. Veenhoven; Elisabeth A. M. Sanders

doi:10.1371/journal.pone.0060520

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Open Access

Peer-reviewed

Research Article

Superiority of Trans-Oral over Trans-Nasal Sampling in Detecting Streptococcus pneumoniae Colonization in Adults

Krzysztof Trzciński ,

* E-mail: K.Trzcinski@umcutrecht.nl

Affiliation Department of Pediatric Immunology and Infectious Diseases, Wilhelmina's Children Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Debby Bogaert,

Affiliation Department of Pediatric Immunology and Infectious Diseases, Wilhelmina's Children Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Anne Wyllie,

Affiliation Department of Pediatric Immunology and Infectious Diseases, Wilhelmina's Children Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Mei Ling J. N. Chu,

Affiliation Department of Pediatric Immunology and Infectious Diseases, Wilhelmina's Children Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Arie van der Ende,

Affiliation Department of Medical Microbiology and The Netherlands Reference Laboratory for Bacterial Meningitis, Academic Medical Centre, Amsterdam, The Netherlands
⨯
Jacob P. Bruin,

Affiliation Regional Laboratory of Public Health, Haarlem, The Netherlands
⨯
Germie van den Dobbelsteen,

Current address: Crucell Nederland, Leiden, The Netherlands

Affiliation Unit Vaccinology, Centre for Infectious Disease Control, The Netherlands Vaccine Institute, Bilthoven, The Netherlands
⨯
Reinier H. Veenhoven,

Affiliation Linnaeus Institute, Spaarne Hospital, Hoofddorp, The Netherlands
⨯
Elisabeth A. M. Sanders

Affiliation Department of Pediatric Immunology and Infectious Diseases, Wilhelmina's Children Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
⨯

Superiority of Trans-Oral over Trans-Nasal Sampling in Detecting Streptococcus pneumoniae Colonization in Adults

Krzysztof Trzciński,
Debby Bogaert,
Anne Wyllie,
Mei Ling J. N. Chu,
Arie van der Ende,
Jacob P. Bruin,
Germie van den Dobbelsteen,
Reinier H. Veenhoven,
Elisabeth A. M. Sanders

Published: March 28, 2013
https://doi.org/10.1371/journal.pone.0060520

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