The Alkaloid Compound Harmane Increases the Lifespan of Caenorhabditis elegans during Bacterial Infection, by Modulating the Nematode’s Innate Immune Response

• Henrik Jakobsen ,

  Contributed equally to this work with: Henrik Jakobsen, Martin S. Bojer

  Affiliations Department of Science, Systems and Models, Roskilde University, Roskilde, Denmark, Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark

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• Martin S. Bojer ,

  Contributed equally to this work with: Henrik Jakobsen, Martin S. Bojer

  Affiliations Department of Science, Systems and Models, Roskilde University, Roskilde, Denmark, Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark

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• Martin G. Marinus,

  Affiliation Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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• Tao Xu,

  Affiliation Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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• Carsten Struve,

  Affiliation Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark

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• Karen A. Krogfelt,

  Affiliation Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark

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• Anders Løbner-Olesen

  * E-mail: lobner@bio.ku.dk

  Affiliation Department of Biology, University of Copenhagen, Copenhagen, Denmark

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