Novel Molecular Pathways Elicited by Mutant FGFR2 May Account for Brain Abnormalities in Apert Syndrome

Erika Yeh; Roberto D. Fanganiello; Daniele Y. Sunaga; Xueyan Zhou; Gregory Holmes; Katia M. Rocha; Nivaldo Alonso; Hamilton Matushita; Yingli Wang; Ethylin W. Jabs; Maria Rita Passos-Bueno

doi:10.1371/journal.pone.0060439

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Open Access

Peer-reviewed

Research Article

Novel Molecular Pathways Elicited by Mutant FGFR2 May Account for Brain Abnormalities in Apert Syndrome

Erika Yeh,

Affiliation Human Genome Center, Department of Genetics and Evolutive Biology, Institute of Bioscience, University of Sao Paulo, Sao Paulo, SP, Brazil
⨯
Roberto D. Fanganiello,

Affiliation Human Genome Center, Department of Genetics and Evolutive Biology, Institute of Bioscience, University of Sao Paulo, Sao Paulo, SP, Brazil
⨯
Daniele Y. Sunaga,

Affiliation Human Genome Center, Department of Genetics and Evolutive Biology, Institute of Bioscience, University of Sao Paulo, Sao Paulo, SP, Brazil
⨯
Xueyan Zhou,

Affiliation Department of Genetics and Genomic Sciences, The Mount Sinai Medical Center, New York, New York, United States of America
⨯
Gregory Holmes,

Affiliation Department of Genetics and Genomic Sciences, The Mount Sinai Medical Center, New York, New York, United States of America
⨯
Katia M. Rocha,

Affiliation Human Genome Center, Department of Genetics and Evolutive Biology, Institute of Bioscience, University of Sao Paulo, Sao Paulo, SP, Brazil
⨯
Nivaldo Alonso,

Affiliation Department of Plastic Surgery, Faculty of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil
⨯
Hamilton Matushita,

Affiliation Department of Neurology, Faculty of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil
⨯
Yingli Wang,

Affiliation Department of Genetics and Genomic Sciences, The Mount Sinai Medical Center, New York, New York, United States of America
⨯
Ethylin W. Jabs,

Affiliation Department of Genetics and Genomic Sciences, The Mount Sinai Medical Center, New York, New York, United States of America
⨯
Maria Rita Passos-Bueno

* E-mail: passos@ib.usp.br

Affiliation Human Genome Center, Department of Genetics and Evolutive Biology, Institute of Bioscience, University of Sao Paulo, Sao Paulo, SP, Brazil
⨯

Novel Molecular Pathways Elicited by Mutant FGFR2 May Account for Brain Abnormalities in Apert Syndrome

Erika Yeh,
Roberto D. Fanganiello,
Daniele Y. Sunaga,
Xueyan Zhou,
Gregory Holmes,
Katia M. Rocha,
Nivaldo Alonso,
Hamilton Matushita,
Yingli Wang,
Ethylin W. Jabs

Published: April 4, 2013
https://doi.org/10.1371/journal.pone.0060439

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