A Novel PEGylated Liposome-Encapsulated SANT75 Suppresses Tumor Growth through Inhibiting Hedgehog Signaling Pathway

Yike Yuan; Yuwei Zhao; Shengchang Xin; Ni Wu; Jiaolin Wen; Song Li; Lijuan Chen; Yuquan Wei; Hanshuo Yang; Shuo Lin

doi:10.1371/journal.pone.0060266

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Open Access

Peer-reviewed

Research Article

A Novel PEGylated Liposome-Encapsulated SANT75 Suppresses Tumor Growth through Inhibiting Hedgehog Signaling Pathway

Yike Yuan,

Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China
⨯
Yuwei Zhao,

Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China
⨯
Shengchang Xin,

Affiliation Laboratory of Chemical Genomics, Shenzhen Graduate School of Peking University, Shenzhen, People's Republic of China
⨯
Ni Wu,

Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China
⨯
Jiaolin Wen,

Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China
⨯
Song Li,

Affiliation Laboratory of Chemical Genomics, Shenzhen Graduate School of Peking University, Shenzhen, People's Republic of China
⨯
Lijuan Chen,

Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China
⨯
Yuquan Wei,

Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China
⨯
Hanshuo Yang ,

* E-mail: yhansh@scu.edu.cn (HY); shuolin@ucla.edu (SL)

Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China
⨯
Shuo Lin

* E-mail: yhansh@scu.edu.cn (HY); shuolin@ucla.edu (SL)

Affiliations State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic of China, Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, United States of America
⨯

A Novel PEGylated Liposome-Encapsulated SANT75 Suppresses Tumor Growth through Inhibiting Hedgehog Signaling Pathway

Yike Yuan,
Yuwei Zhao,
Shengchang Xin,
Ni Wu,
Jiaolin Wen,
Song Li,
Lijuan Chen,
Yuquan Wei,
Hanshuo Yang,
Shuo Lin

Published: April 1, 2013
https://doi.org/10.1371/journal.pone.0060266

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