Site Specific Mutation of the Zic2 Locus by Microinjection of TALEN mRNA in Mouse CD1, C3H and C57BL/6J Oocytes

Open Access

Peer-reviewed

Research Article

Benjamin Davies ,

* E-mail: ben.davies@well.ox.ac.uk

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Graham Davies,

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
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Christopher Preece,

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Rathi Puliyadi,

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
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Dorota Szumska,

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
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Shoumo Bhattacharya

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
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TALENs
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Mouse models
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Mutagenesis
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Microinjection
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Nonsense mutation
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Mammalian genomics
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Oocytes
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Zinc finger nucleases
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