Association between P16INK4a Promoter Methylation and Non-Small Cell Lung Cancer: A Meta-Analysis

Jundong Gu; Yanjun Wen; Siwei Zhu; Feng Hua; Hui Zhao; Hongrui Xu; Jiacong You; Linlin Sun; Weiqiang Wang; Jun Chen; Qinghua Zhou

doi:10.1371/journal.pone.0060107

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Open Access

Peer-reviewed

Research Article

Association between P^16INK4a Promoter Methylation and Non-Small Cell Lung Cancer: A Meta-Analysis

Jundong Gu ,

Contributed equally to this work with: Jundong Gu, Yanjun Wen

Affiliations Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China, Department of Thoracic Surgery, Tianjin Union Medical Center, Tianjin, China
⨯
Yanjun Wen ,

Contributed equally to this work with: Jundong Gu, Yanjun Wen

Affiliation Department of Neuropathology, Neurology Institute, Tianjin Medical University General Hospital, Tianjin, China
⨯
Siwei Zhu,

Affiliation Department of Oncology, Tianjin Union Medical Center, Tianjin, China
⨯
Feng Hua,

Affiliation Department of Thoracic Surgery, Shandong Cancer Hospital, Shandong, China
⨯
Hui Zhao,

Affiliation Department of Thoracic Surgery, Tianjin Union Medical Center, Tianjin, China
⨯
Hongrui Xu,

Affiliation Department of Thoracic Surgery, Tianjin Union Medical Center, Tianjin, China
⨯
Jiacong You,

Affiliation Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China
⨯
Linlin Sun,

Affiliation Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China
⨯
Weiqiang Wang,

Affiliation Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China
⨯
Jun Chen,

Affiliation Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China
⨯
Qinghua Zhou

* E-mail: zhouqh1016@yahoo.com.cn

Affiliation Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China
⨯

Association between P^16INK4a Promoter Methylation and Non-Small Cell Lung Cancer: A Meta-Analysis

Jundong Gu,
Yanjun Wen,
Siwei Zhu,
Feng Hua,
Hui Zhao,
Hongrui Xu,
Jiacong You,
Linlin Sun,
Weiqiang Wang,
Jun Chen

Published: April 5, 2013
https://doi.org/10.1371/journal.pone.0060107

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Non-small cell lung cancer
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Methylation
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DNA methylation
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Sputum
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Metaanalysis
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Lung and intrathoracic tumors
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Cancer detection and diagnosis
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Tumor suppressor genes
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