A Randomized Controlled Trial of the Efficacy and Safety of CCX282-B, an Orally-Administered Blocker of Chemokine Receptor CCR9, for Patients with Crohn’s Disease

• Satish Keshav,

  Affiliation John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom

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• Tomáš Vaňásek,

  Affiliation Hepato-Gastroenterologie HK, Hradec Králové, Czech Republic

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• Yaron Niv,

  Affiliation Rabin Medical Center, Petach Tikva, Israel

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• Robert Petryka,

  Affiliation NZOZ Vivamed, Zespół Lekarzy Specjalistów, Warszawa, Poland

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• Stephanie Howaldt,

  Affiliation Praxis für Innere Medizin, Hamburg, Germany

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• Mauro Bafutto,

  Affiliation Instituto Goiano de Gastroenterologia e Endoscopia Digestiva Ltda., Goiânia, Brazil

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• István Rácz,

  Affiliation Petz Aladár County and Teaching Hospital, Győr, Hungary

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• David Hetzel,

  Affiliation Royal Adelaide Hospital, Adelaide, Australia

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• Ole Haagen Nielsen,

  Affiliation Department of Gastroenterology, Herlev Hospital, Herlev, Denmark

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• Séverine Vermeire,

  Affiliation UZ Gasthuisberg, Leuven, Belgium

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• Walter Reinisch,

  Affiliation Allgemeines Krankenhaus Wien, Universitätsklinik für Innere Medizin III, Klinische Abteilung für Gastroenterologie und Hepatologie, Vienna, Austria

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• Per Karlén,

  Affiliation Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden

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• Stefan Schreiber,

  Affiliation Department of Medicine I, Christian Albrechts University, University Hospital Schleswig Holstein, Kiel, Germany

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• Thomas J. Schall,

  Affiliation ChemoCentryx, Inc., Mountain View, California, United States of America

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• Pirow Bekker, for the Prospective Randomized Oral-Therapy Evaluation in Crohn’s Disease Trial-1 (PROTECT-1) Study Group

  * E-mail: pbekker@chemocentryx.com

  The investigators who contributed to the Prospective Randomized Oral-Therapy Evaluation in Crohn’s Disease Trial-1 (PROTECT-1) are listed in Appendix S1.

  Affiliation ChemoCentryx, Inc., Mountain View, California, United States of America

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