Characterization of SNPs Associated with Prostate Cancer in Men of Ashkenazic Descent from the Set of GWAS Identified SNPs: Impact of Cancer Family History and Cumulative SNP Risk Prediction

Ilir Agalliu; Zhaoming Wang; Tao Wang; Anne Dunn; Hemang Parikh; Timothy Myers; Robert D. Burk; Laufey Amundadottir

doi:10.1371/journal.pone.0060083

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Open Access

Peer-reviewed

Research Article

Characterization of SNPs Associated with Prostate Cancer in Men of Ashkenazic Descent from the Set of GWAS Identified SNPs: Impact of Cancer Family History and Cumulative SNP Risk Prediction

Ilir Agalliu ,

* E-mail: ilir.agalliu@einstein.yu.edu

Affiliation Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Zhaoming Wang,

Affiliation Cancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Tao Wang,

Affiliation Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Anne Dunn,

Affiliation Department of Pediatrics (Genetics), Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Hemang Parikh,

Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Timothy Myers,

Affiliations Cancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Robert D. Burk ,

Contributed equally to this work with: Robert D. Burk, Laufey Amundadottir

Affiliations Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Pediatrics (Genetics), Albert Einstein College of Medicine, Bronx, New York, United States of America, Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Obstetrics, Gynecology and Women’s Health, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Laufey Amundadottir

Contributed equally to this work with: Robert D. Burk, Laufey Amundadottir

Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Characterization of SNPs Associated with Prostate Cancer in Men of Ashkenazic Descent from the Set of GWAS Identified SNPs: Impact of Cancer Family History and Cumulative SNP Risk Prediction

Ilir Agalliu,
Zhaoming Wang,
Tao Wang,
Anne Dunn,
Hemang Parikh,
Timothy Myers,
Robert D. Burk,
Laufey Amundadottir

Published: April 3, 2013
https://doi.org/10.1371/journal.pone.0060083

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Cancer risk factors
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Prostate cancer
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Single nucleotide polymorphisms
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Genome-wide association studies
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Lung and intrathoracic tumors
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Cancer detection and diagnosis
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Variant genotypes
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