Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship

Chapla Agarwal; Ritambhara Wadhwa; Gagan Deep; David Biedermann; Radek Gažák; Vladimír Křen; Rajesh Agarwal

doi:10.1371/journal.pone.0060074

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Open Access

Peer-reviewed

Research Article

Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship

Chapla Agarwal,

Affiliations Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America, University of Colorado Cancer Center, Anschutz Medical Campus, University of Colorado, Aurora, Colorado, United States of America
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Ritambhara Wadhwa,

Affiliation Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America
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Gagan Deep,

Affiliations Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America, University of Colorado Cancer Center, Anschutz Medical Campus, University of Colorado, Aurora, Colorado, United States of America
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David Biedermann,

Affiliation Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
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Radek Gažák,

Affiliation Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
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Vladimír Křen,

Affiliation Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
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Rajesh Agarwal

* E-mail: Rajesh.Agarwal@UCDenver.edu

Affiliations Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America, University of Colorado Cancer Center, Anschutz Medical Campus, University of Colorado, Aurora, Colorado, United States of America
⨯

Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship

Chapla Agarwal,
Ritambhara Wadhwa,
Gagan Deep,
David Biedermann,
Radek Gažák,
Vladimír Křen,
Rajesh Agarwal

Published: March 28, 2013
https://doi.org/10.1371/journal.pone.0060074

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30 May 2014
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diastereomeric kinetic resolution Posted by chemboy on 29 May 2014 at 15:18 GMT

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