Relationships between Clinicopathological Features and Cerebrospinal Fluid Biomarkers in Japanese Patients with Genetic Prion Diseases

Maya Higuma; Nobuo Sanjo; Katsuya Satoh; Yusei Shiga; Kenji Sakai; Ichiro Nozaki; Tsuyoshi Hamaguchi; Yosikazu Nakamura; Tetsuyuki Kitamoto; Susumu Shirabe; Shigeo Murayama; Masahito Yamada; Jun Tateishi; Hidehiro Mizusawa

doi:10.1371/journal.pone.0060003

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Open Access

Peer-reviewed

Research Article

Relationships between Clinicopathological Features and Cerebrospinal Fluid Biomarkers in Japanese Patients with Genetic Prion Diseases

Maya Higuma,

Affiliation Department of Neurology and Neurological Science, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan
⨯
Nobuo Sanjo ,

* E-mail: n-sanjo.nuro@tmd.ac.jp

Affiliation Department of Neurology and Neurological Science, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan
⨯
Katsuya Satoh,

Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Yusei Shiga,

Affiliation Department of Neurology, Aoba Neurosurgical Hospital, Sendai, Japan
⨯
Kenji Sakai,

Affiliation Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
⨯
Ichiro Nozaki,

Affiliation Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
⨯
Tsuyoshi Hamaguchi,

Affiliation Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
⨯
Yosikazu Nakamura,

Affiliation Department of Public Health, Jichi Medical University, Tochigi, Japan
⨯
Tetsuyuki Kitamoto,

Affiliation Department of Prion Protein Research, Division of CJD Science and Technology, Tohoku University Graduate School of Medicine, Miyagi, Japan
⨯
Susumu Shirabe,

Affiliation Center for Health and Community Medicine, Nagasaki University Hospital, Nagasaki, Japan
⨯
Shigeo Murayama,

Affiliation Department of Neuropathology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
⨯
Masahito Yamada,

Affiliation Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
⨯
Jun Tateishi,

Affiliation Harukaze Healthcare Service Institution, Fukuoka, Japan
⨯
Hidehiro Mizusawa

Affiliation Department of Neurology and Neurological Science, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan
⨯

Relationships between Clinicopathological Features and Cerebrospinal Fluid Biomarkers in Japanese Patients with Genetic Prion Diseases

Maya Higuma,
Nobuo Sanjo,
Katsuya Satoh,
Yusei Shiga,
Kenji Sakai,
Ichiro Nozaki,
Tsuyoshi Hamaguchi,
Yosikazu Nakamura,
Tetsuyuki Kitamoto,
Susumu Shirabe

Published: March 28, 2013
https://doi.org/10.1371/journal.pone.0060003

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