The Co-Repressor SMRT Delays DNA Damage-Induced Caspase Activation by Repressing Pro-Apoptotic Genes and Modulating the Dynamics of Checkpoint Kinase 2 Activation

• Claudio Scafoglio ,

  * E-mail: cscafoglio@mednet.ucla.edu (CS); mrosenfeld@ucsd.edu (MGR)

  Affiliations Howard Hughes Medical Institute and School of Medicine, University of California San Diego, La Jolla, California, United States of America, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

  ⨯
• Marcus Smolka,

  Affiliations Ludwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America

  ⨯
• Huilin Zhou,

  Affiliation Ludwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Valentina Perissi,

  Affiliations Howard Hughes Medical Institute and School of Medicine, University of California San Diego, La Jolla, California, United States of America, School of Medicine, Boston University, Boston, Massachusetts, United States of America

  ⨯
• Michael G. Rosenfeld

  * E-mail: cscafoglio@mednet.ucla.edu (CS); mrosenfeld@ucsd.edu (MGR)

  Affiliations Howard Hughes Medical Institute and School of Medicine, University of California San Diego, La Jolla, California, United States of America, Ludwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯