Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain

• Wei Wu,

  Affiliation Department of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia

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• Joseph A. Nicolazzo,

  Affiliation Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia

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• Li Wen,

  Affiliation Cornea and NSW Eye Bank, The University of Sydney, Sydney, New South Wales, Australia

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• Roger Chung,

  Affiliation Menzies Research Institute Tasmania, The University of Tasmania, Hobart, Tasmania, Australia

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• Roger Stankovic,

  Affiliation Discipline of Pathology, The University of Sydney, Sydney, New South Wales, Australia

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• Shisan S. Bao,

  Affiliation Discipline of Pathology, The University of Sydney, Sydney, New South Wales, Australia

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• Chai K. Lim,

  Affiliations Department of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia, MND and Neurodegenerative Disease Research Group, Macquarie University, North Ryde, New South Wales, Australia

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• Bruce J. Brew,

  Affiliations St Vincent's Centre for Applied Medical Research, Darlinghurst, New South Wales, Australia, Departments of Neurology and HIV Medicine, St. Vincent's Hospital, Darlinghurst, New South Wales, Australia

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• Karen M. Cullen ,

  Contributed equally to this work with: Karen M. Cullen, Gilles J. Guillemin

  Affiliation Discipline of Anatomy and Histology, The University of Sydney, Sydney, New South Wales, Australia

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• Gilles J. Guillemin

  Contributed equally to this work with: Karen M. Cullen, Gilles J. Guillemin

  * E-mail: gilles.guillemin@mq.edu.au

  Affiliations Department of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia, MND and Neurodegenerative Disease Research Group, Macquarie University, North Ryde, New South Wales, Australia

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