Targeted Induction of Interferon-λ in Humanized Chimeric Mouse Liver Abrogates Hepatotropic Virus Infection

• Shin-ichiro Nakagawa ,

  Contributed equally to this work with: Shin-ichiro Nakagawa, Yuichi Hirata

  Affiliations Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan, Discovery Research Laboratories, Nippon Shinyaku Co., Ltd., Tsukuba, Ibaraki, Japan

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• Yuichi Hirata ,

  Contributed equally to this work with: Shin-ichiro Nakagawa, Yuichi Hirata

  Affiliations Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan, Division of Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan

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• Takeshi Kameyama,

  Affiliation Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

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• Yuko Tokunaga,

  Affiliation Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

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• Yasumasa Nishito,

  Affiliation Center for Microarray Analysis, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

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• Kazuko Hirabayashi,

  Affiliation Discovery Research Laboratories, Nippon Shinyaku Co., Ltd., Tsukuba, Ibaraki, Japan

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• Junichi Yano,

  Affiliation Discovery Research Laboratories, Nippon Shinyaku Co., Ltd., Tsukuba, Ibaraki, Japan

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• Takahiro Ochiya,

  Affiliation Division of Molecular and Cellular Medicine, Japanese National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan

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• Chise Tateno,

  Affiliation PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan

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• Yasuhito Tanaka,

  Affiliation Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Science, Nagoya, Aichi, Japan

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• Masashi Mizokami,

  Affiliation Research Center for Hepatitis and Immunology, International Medical Center of Japan Konodai Hospital, Ichikawa, Chiba, Japan

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• Kyoko Tsukiyama-Kohara,

  Affiliation Transboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan

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• Kazuaki Inoue,

  Affiliation Division of Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan

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• Makoto Yoshiba,

  Affiliation Division of Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan

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• Akinori Takaoka,

  Affiliation Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

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•  [ ... ],
• Michinori Kohara

  * E-mail: kohara-mc@igakuken.or.jp

  Affiliation Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

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