Abnormal Apoptosis of Trophoblastic Cells Is Related to the Up-Regulation of CYP11A Gene in Placenta of Preeclampsia Patients

Guolin He; Wenming Xu; Yan Chen; Xinghui Liu; Mingrong Xi

doi:10.1371/journal.pone.0059609

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Peer-reviewed

Research Article

Abnormal Apoptosis of Trophoblastic Cells Is Related to the Up-Regulation of CYP11A Gene in Placenta of Preeclampsia Patients

Guolin He ,

Contributed equally to this work with: Guolin He, Wenming Xu

Affiliations Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China, Joint Laboratory for Reproductive Medicine, Sichuan University-The Chinese University of Hong Kong (SCU-CUHK), West China Second University Hospital, Sichuan University, Chengdu, China
⨯
Wenming Xu ,

Contributed equally to this work with: Guolin He, Wenming Xu

Affiliations Joint Laboratory for Reproductive Medicine, Sichuan University-The Chinese University of Hong Kong (SCU-CUHK), West China Second University Hospital, Sichuan University, Chengdu, China, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China
⨯
Yan Chen,

Affiliations Joint Laboratory for Reproductive Medicine, Sichuan University-The Chinese University of Hong Kong (SCU-CUHK), West China Second University Hospital, Sichuan University, Chengdu, China, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China
⨯
Xinghui Liu ,

* E-mail: Xinghuiliu@163.com (XL); qmrjzz@126.com (MX)

Affiliation Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China
⨯
Mingrong Xi

* E-mail: Xinghuiliu@163.com (XL); qmrjzz@126.com (MX)

Affiliation Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China
⨯

Abnormal Apoptosis of Trophoblastic Cells Is Related to the Up-Regulation of CYP11A Gene in Placenta of Preeclampsia Patients

Guolin He,
Wenming Xu,
Yan Chen,
Xinghui Liu,
Mingrong Xi

Published: March 29, 2013
https://doi.org/10.1371/journal.pone.0059609

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Preeclampsia
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Pregnancy
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Apoptosis
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Placenta
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Trophoblasts
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Gene expression
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Protein expression
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Hyperexpression techniques
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