Promyelocytic Leukemia (PML) Protein Plays Important Roles in Regulating Cell Adhesion, Morphology, Proliferation and Migration

Mei Kuen Tang; Yong Jia Liang; John Yeuk Hon Chan; Sing Wan Wong; Elve Chen; Yao Yao; Jingyi Gan; Lihai Xiao; Hin Cheung Leung; Hsiang Fu Kung; Hua Wang; Kenneth Ka Ho Lee

doi:10.1371/journal.pone.0059477

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Open Access

Peer-reviewed

Research Article

Promyelocytic Leukemia (PML) Protein Plays Important Roles in Regulating Cell Adhesion, Morphology, Proliferation and Migration

Mei Kuen Tang ,

* E-mail: florencetang@cuhk.edu.hk (MKT); kaholee@cuhk.edu.hk (KKHL)

Affiliation Stem Cell and Regeneration Thematic Research Programme, School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Yong Jia Liang,

Affiliation Joint JNU-CUHK Key Laboratories for Regenerative Medicine, Ministry of Education, JiNan University, Guangzhou, China
⨯
John Yeuk Hon Chan,

Affiliation Joint JNU-CUHK Key Laboratories for Regenerative Medicine, Ministry of Education, JiNan University, Guangzhou, China
⨯
Sing Wan Wong,

Affiliation Stem Cell and Regeneration Thematic Research Programme, School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Elve Chen,

Affiliation Stem Cell and Regeneration Thematic Research Programme, School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Yao Yao,

Affiliation Stem Cell and Regeneration Thematic Research Programme, School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Jingyi Gan,

Affiliation Stem Cell and Regeneration Thematic Research Programme, School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Lihai Xiao,

Affiliation Stem Cell and Regeneration Thematic Research Programme, School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Hin Cheung Leung,

Affiliation Stem Cell and Regeneration Thematic Research Programme, School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Hsiang Fu Kung,

Affiliation Division of Infectious Diseases, School of Public Health and Primary Care, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Hua Wang,

Affiliation Division of Infectious Diseases, School of Public Health and Primary Care, Chinese University of Hong Kong, Shatin, N.T., Hong Kong
⨯
Kenneth Ka Ho Lee

* E-mail: florencetang@cuhk.edu.hk (MKT); kaholee@cuhk.edu.hk (KKHL)

Affiliations Stem Cell and Regeneration Thematic Research Programme, School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, N.T., Hong Kong, Joint JNU-CUHK Key Laboratories for Regenerative Medicine, Ministry of Education, JiNan University, Guangzhou, China
⨯

Promyelocytic Leukemia (PML) Protein Plays Important Roles in Regulating Cell Adhesion, Morphology, Proliferation and Migration

Mei Kuen Tang,
Yong Jia Liang,
John Yeuk Hon Chan,
Sing Wan Wong,
Elve Chen,
Yao Yao,
Jingyi Gan,
Lihai Xiao,
Hin Cheung Leung,
Hsiang Fu Kung

Published: March 21, 2013
https://doi.org/10.1371/journal.pone.0059477

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Membrane proteins
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Phosphorylation
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Nuclear staining
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Transfection
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Reverse transcriptase-polymerase chain reaction
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Synthesis phase
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Cell proliferation
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Cytoplasmic staining
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