RNA-Dependent Protein Kinase Is Essential for 2-Methoxyestradiol-Induced Autophagy in Osteosarcoma Cells

Open Access

Peer-reviewed

Research Article

Caihong Yang,

Affiliations Department of Orthopedics, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Orthopedic, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Kristen L. Shogren,

Affiliation Department of Orthopedics, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Ribu Goyal,

Affiliation Department of Orthopedics, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Dalibel Bravo,

Affiliation Department of Orthopedics, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Michael J. Yaszemski,

Affiliation Department of Orthopedics, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Avudaiappan Maran

* E-mail: maran.avudai@mayo.edu

Affiliation Department of Orthopedics, Mayo Clinic, Rochester, Minnesota, United States of America
⨯

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Autophagic cell death
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Osteosarcoma cells
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Proteolysis
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Small interfering RNA
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Transfection
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Apoptosis
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Transmission electron microscopy
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Cancer treatment
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