Longer Telomere Length in Peripheral White Blood Cells Is Associated with Risk of Lung Cancer and the rs2736100 (CLPTM1L-TERT) Polymorphism in a Prospective Cohort Study among Women in China

Qing Lan; Richard Cawthon; Yutang Gao; Wei Hu; H. Dean Hosgood III; Francesco Barone-Adesi; Bu-Tian Ji; Bryan Bassig; Wong-Ho Chow; Xiaoou Shu; Qiuyin Cai; Yongbin Xiang; Sonja Berndt; Christopher Kim; Stephen Chanock; Wei Zheng; Nathaniel Rothman

doi:10.1371/journal.pone.0059230

Loading metrics

Open Access

Peer-reviewed

Research Article

Longer Telomere Length in Peripheral White Blood Cells Is Associated with Risk of Lung Cancer and the rs2736100 (CLPTM1L-TERT) Polymorphism in a Prospective Cohort Study among Women in China

Qing Lan ,

* E-mail: qingl@mail.nih.gov

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Richard Cawthon,

Affiliation Department of Human Genetics, University of Utah, Salt Lake City, Utah, United States of America
⨯
Yutang Gao,

Affiliation Department of Epidemiology, Shanghai Cancer Institute, Shanghai, Peoples Republic of China
⨯
Wei Hu,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
H. Dean Hosgood III,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Francesco Barone-Adesi,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Bu-Tian Ji,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Bryan Bassig,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Wong-Ho Chow,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Xiaoou Shu,

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States of America
⨯
Qiuyin Cai,

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States of America
⨯
Yongbin Xiang,

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States of America
⨯
Sonja Berndt,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Christopher Kim,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Stephen Chanock,

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
Wei Zheng,

Affiliation Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States of America
⨯
[ ... ],
Nathaniel Rothman

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, United States of America
⨯
[ view all ]
[ view less ]

Longer Telomere Length in Peripheral White Blood Cells Is Associated with Risk of Lung Cancer and the rs2736100 (CLPTM1L-TERT) Polymorphism in a Prospective Cohort Study among Women in China

Qing Lan,
Richard Cawthon,
Yutang Gao,
Wei Hu,
H. Dean Hosgood III,
Francesco Barone-Adesi,
Bu-Tian Ji,
Bryan Bassig,
Wong-Ho Chow,
Xiaoou Shu

Published: March 26, 2013
https://doi.org/10.1371/journal.pone.0059230

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Telomere length
Is the Subject Area "Telomere length" applicable to this article?

Thanks for your feedback.
Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Telomeres
Is the Subject Area "Telomeres" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Cohort studies
Is the Subject Area "Cohort studies" applicable to this article?

Thanks for your feedback.
Colorectal cancer
Is the Subject Area "Colorectal cancer" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.