Continuous and Discontinuous Cigarette Smoke Exposure Differentially Affects Protective Th1 Immunity against Pulmonary Tuberculosis

Christopher R. Shaler; Carly N. Horvath; Sarah McCormick; Mangalakumari Jeyanathan; Amandeep Khera; Anna Zganiacz; Joanna Kasinska; Martin R. Stampfli; Zhou Xing

doi:10.1371/journal.pone.0059185

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Open Access

Peer-reviewed

Research Article

Continuous and Discontinuous Cigarette Smoke Exposure Differentially Affects Protective Th1 Immunity against Pulmonary Tuberculosis

Christopher R. Shaler,

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Carly N. Horvath,

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Sarah McCormick,

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Mangalakumari Jeyanathan,

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Amandeep Khera,

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Anna Zganiacz,

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Joanna Kasinska,

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Martin R. Stampfli ,

* E-mail: stampfli@mcmaster.ca (MRS); xingz@mcmaster.ca (ZX)

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Zhou Xing

* E-mail: stampfli@mcmaster.ca (MRS); xingz@mcmaster.ca (ZX)

Affiliation McMaster Immunology Research Centre, and Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
⨯

Continuous and Discontinuous Cigarette Smoke Exposure Differentially Affects Protective Th1 Immunity against Pulmonary Tuberculosis

Christopher R. Shaler,
Carly N. Horvath,
Sarah McCormick,
Mangalakumari Jeyanathan,
Amandeep Khera,
Anna Zganiacz,
Joanna Kasinska,
Martin R. Stampfli,
Zhou Xing

Published: March 19, 2013
https://doi.org/10.1371/journal.pone.0059185

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