MLH1 Promoter Methylation Frequency in Colorectal Cancer Patients and Related Clinicopathological and Molecular Features

Xia Li; Xiaoping Yao; Yibaina Wang; Fulan Hu; Fan Wang; Liying Jiang; Yupeng Liu; Da Wang; Guizhi Sun; Yashuang Zhao

doi:10.1371/journal.pone.0059064

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Open Access

Peer-reviewed

Research Article

MLH1 Promoter Methylation Frequency in Colorectal Cancer Patients and Related Clinicopathological and Molecular Features

Xia Li,

Affiliation Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Xiaoping Yao,

Affiliation Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Yibaina Wang,

Affiliation Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Fulan Hu,

Affiliation Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Fan Wang,

Affiliation Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Liying Jiang,

Affiliation Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Yupeng Liu,

Affiliation Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Da Wang,

Affiliation Department of Science and Technology Administration, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Guizhi Sun,

Affiliation Department of Surgery, Cancer Hospital of Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯
Yashuang Zhao

* E-mail: zhao_yashuang@263.net

Affiliation Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, P.R. China
⨯

MLH1 Promoter Methylation Frequency in Colorectal Cancer Patients and Related Clinicopathological and Molecular Features

Xia Li,
Xiaoping Yao,
Yibaina Wang,
Fulan Hu,
Fan Wang,
Liying Jiang,
Yupeng Liu,
Da Wang,
Guizhi Sun,
Yashuang Zhao

Published: March 29, 2013
https://doi.org/10.1371/journal.pone.0059064

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Colorectal cancer
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Methylation
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DNA methylation
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Protein expression
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Cancers and neoplasms
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Metaanalysis
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Differentiated tumors
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