Increased Sensitivity to Chemotherapy Induced by CpG-ODN Treatment Is Mediated by microRNA Modulation

Loris De Cecco; Martina Berardi; Michele Sommariva; Alessandra Cataldo; Silvana Canevari; Delia Mezzanzanica; Marilena V. Iorio; Elda Tagliabue; Andrea Balsari

doi:10.1371/journal.pone.0058849

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Peer-reviewed

Research Article

Increased Sensitivity to Chemotherapy Induced by CpG-ODN Treatment Is Mediated by microRNA Modulation

Loris De Cecco ,

Contributed equally to this work with: Loris De Cecco, Martina Berardi

Affiliation Functional Genomics Core Facility, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Martina Berardi ,

Contributed equally to this work with: Loris De Cecco, Martina Berardi

Affiliation Molecular Targeting Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Michele Sommariva,

Affiliations Molecular Targeting Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy, Department of Biomedical Sciences for Health, University of Milan, Milan, Italy
⨯
Alessandra Cataldo,

Affiliation Department of Biomedical Sciences for Health, University of Milan, Milan, Italy
⨯
Silvana Canevari,

Affiliation Molecular Therapies Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Delia Mezzanzanica,

Affiliation Molecular Therapies Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Marilena V. Iorio,

Affiliation Start Up Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Elda Tagliabue,

Affiliation Molecular Targeting Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy
⨯
Andrea Balsari

* E-mail: andrea.balsari@unimi.it

Affiliations Molecular Targeting Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy, Department of Biomedical Sciences for Health, University of Milan, Milan, Italy
⨯

Increased Sensitivity to Chemotherapy Induced by CpG-ODN Treatment Is Mediated by microRNA Modulation

Loris De Cecco,
Martina Berardi,
Michele Sommariva,
Alessandra Cataldo,
Silvana Canevari,
Delia Mezzanzanica,
Marilena V. Iorio,
Elda Tagliabue,
Andrea Balsari

Published: March 6, 2013
https://doi.org/10.1371/journal.pone.0058849

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MicroRNAs
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Cancer treatment
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Gene expression
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DNA repair
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