Increased Cardiac Myocyte PDE5 Levels in Human and Murine Pressure Overload Hypertrophy Contribute to Adverse LV Remodeling

• Sara Vandenwijngaert,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Peter Pokreisz,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Hadewich Hermans,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Hilde Gillijns,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Marijke Pellens,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Noortje A. M. Bax,

  Affiliation Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

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• Giulia Coppiello,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Wouter Oosterlinck,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Agnes Balogh,

  Affiliation Division of Clinical Physiology, Institute of Cardiology, Research Center for Molecular Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary

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• Zoltan Papp,

  Affiliation Division of Clinical Physiology, Institute of Cardiology, Research Center for Molecular Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary

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• Carlijn V. C. Bouten,

  Affiliation Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

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• Jozef Bartunek,

  Affiliations Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium, Cardiovascular Center, OLV Hospital, Aalst, Belgium

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• Jan D'hooge,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Aernout Luttun,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Erik Verbeken,

  Affiliation Department of Imaging and Pathology, KU Leuven, Leuven, Belgium

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• Marie Christine Herregods,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Paul Herijgers,

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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• Kenneth D. Bloch,

  Affiliation Anesthesia Center for Critical Care Research, Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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•  [ ... ],
• Stefan Janssens

  * E-mail: stefan.janssens@med.kuleuven.be

  Affiliation Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

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