Development of Strategies for SNP Detection in RNA-Seq Data: Application to Lymphoblastoid Cell Lines and Evaluation Using 1000 Genomes Data

Emma M. Quinn; Paul Cormican; Elaine M. Kenny; Matthew Hill; Richard Anney; Michael Gill; Aiden P. Corvin; Derek W. Morris

doi:10.1371/journal.pone.0058815

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Peer-reviewed

Research Article

Development of Strategies for SNP Detection in RNA-Seq Data: Application to Lymphoblastoid Cell Lines and Evaluation Using 1000 Genomes Data

Emma M. Quinn ,

Contributed equally to this work with: Emma M. Quinn, Paul Cormican, Elaine M. Kenny

Affiliation TrinSeq and Neuropsychiatric Genetics Research Group, Department of Psychiatry and Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
⨯
Paul Cormican ,

Contributed equally to this work with: Emma M. Quinn, Paul Cormican, Elaine M. Kenny

Affiliation TrinSeq and Neuropsychiatric Genetics Research Group, Department of Psychiatry and Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
⨯
Elaine M. Kenny ,

Contributed equally to this work with: Emma M. Quinn, Paul Cormican, Elaine M. Kenny

Affiliation TrinSeq and Neuropsychiatric Genetics Research Group, Department of Psychiatry and Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
⨯
Matthew Hill,

Affiliation TrinSeq and Neuropsychiatric Genetics Research Group, Department of Psychiatry and Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
⨯
Richard Anney,

Affiliation TrinSeq and Neuropsychiatric Genetics Research Group, Department of Psychiatry and Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
⨯
Michael Gill,

Affiliation TrinSeq and Neuropsychiatric Genetics Research Group, Department of Psychiatry and Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
⨯
Aiden P. Corvin,

Affiliation TrinSeq and Neuropsychiatric Genetics Research Group, Department of Psychiatry and Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
⨯
Derek W. Morris

* E-mail: derek.morris@tcd.ie

Affiliation TrinSeq and Neuropsychiatric Genetics Research Group, Department of Psychiatry and Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
⨯

Development of Strategies for SNP Detection in RNA-Seq Data: Application to Lymphoblastoid Cell Lines and Evaluation Using 1000 Genomes Data

Emma M. Quinn,
Paul Cormican,
Elaine M. Kenny,
Matthew Hill,
Richard Anney,
Michael Gill,
Aiden P. Corvin,
Derek W. Morris

Published: March 26, 2013
https://doi.org/10.1371/journal.pone.0058815

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Single nucleotide polymorphisms
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Genomics
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Transcriptome analysis
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RNA sequencing
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Sequence alignment
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Genome analysis
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Gene expression
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Genome sequencing
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