Classify Hyperdiploidy Status of Multiple Myeloma Patients Using Gene Expression Profiles

Yingxiang Li; Xujun Wang; Haiyang Zheng; Chengyang Wang; Stéphane Minvielle; Florence Magrangeas; Hervé Avet-Loiseau; Parantu K. Shah; Yong Zhang; Nikhil C. Munshi; Cheng Li

doi:10.1371/journal.pone.0058809

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Open Access

Peer-reviewed

Research Article

Classify Hyperdiploidy Status of Multiple Myeloma Patients Using Gene Expression Profiles

Yingxiang Li ,

Contributed equally to this work with: Yingxiang Li, Xujun Wang

Affiliation Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, China
⨯
Xujun Wang ,

Contributed equally to this work with: Yingxiang Li, Xujun Wang

Affiliation Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, China
⨯
Haiyang Zheng,

Affiliation Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, China
⨯
Chengyang Wang,

Affiliation Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, China
⨯
Stéphane Minvielle,

Affiliation Inserm UMR892, CNRS 6299, Université de Nantes, Centre Hospitalier Universitaire de Nantes, Unité Mixte de Genomique du Cancer, Nantes, France
⨯
Florence Magrangeas,

Affiliation Inserm UMR892, CNRS 6299, Université de Nantes, Centre Hospitalier Universitaire de Nantes, Unité Mixte de Genomique du Cancer, Nantes, France
⨯
Hervé Avet-Loiseau,

Affiliation Inserm UMR892, CNRS 6299, Université de Nantes, Centre Hospitalier Universitaire de Nantes, Unité Mixte de Genomique du Cancer, Nantes, France
⨯
Parantu K. Shah,

Affiliation Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Yong Zhang,

Affiliation Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, China
⨯
Nikhil C. Munshi,

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, and Boston VA Healthcare System, Boston, Massachusetts, United States of America
⨯
Cheng Li

* E-mail: lch3000@gmail.com

Affiliations Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, China, Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯

Classify Hyperdiploidy Status of Multiple Myeloma Patients Using Gene Expression Profiles

Yingxiang Li,
Xujun Wang,
Haiyang Zheng,
Chengyang Wang,
Stéphane Minvielle,
Florence Magrangeas,
Hervé Avet-Loiseau,
Parantu K. Shah,
Yong Zhang,
Nikhil C. Munshi

Published: March 15, 2013
https://doi.org/10.1371/journal.pone.0058809

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Hidden Markov models
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Multiple myeloma
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Gene expression
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Prognosis
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Microarrays
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Cancers and neoplasms
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Fluorescent in situ hybridization
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Chromosomal deletions
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