Spry1 and Spry4 Differentially Regulate Human Aortic Smooth Muscle Cell Phenotype via Akt/FoxO/Myocardin Signaling

Xuehui Yang; Yan Gong; Yuefeng Tang; Hongfang Li; Qing He; Lindsey Gower; Lucy Liaw; Robert E. Friesel

doi:10.1371/journal.pone.0058746

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Peer-reviewed

Research Article

Spry1 and Spry4 Differentially Regulate Human Aortic Smooth Muscle Cell Phenotype via Akt/FoxO/Myocardin Signaling

Xuehui Yang ,

* E-mail: yangx@mmc.org (XY); friesr@mmc.org (RF)

Affiliation Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America
⨯
Yan Gong,

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America, Graduate School for Biomedical Sciences, University of Maine, Orono, Maine, United States of America
⨯
Yuefeng Tang,

Current address: Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America, Graduate School for Biomedical Sciences, University of Maine, Orono, Maine, United States of America
⨯
Hongfang Li,

Affiliation Department of Physiology, College of Basic Medicine, Lanzhou University, Lanzhou, China
⨯
Qing He,

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America, Graduate School for Biomedical Sciences, University of Maine, Orono, Maine, United States of America
⨯
Lindsey Gower,

Affiliation Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America
⨯
Lucy Liaw,

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America, Graduate School for Biomedical Sciences, University of Maine, Orono, Maine, United States of America
⨯
Robert E. Friesel

* E-mail: yangx@mmc.org (XY); friesr@mmc.org (RF)

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America, Graduate School for Biomedical Sciences, University of Maine, Orono, Maine, United States of America
⨯

Spry1 and Spry4 Differentially Regulate Human Aortic Smooth Muscle Cell Phenotype via Akt/FoxO/Myocardin Signaling

Xuehui Yang,
Yan Gong,
Yuefeng Tang,
Hongfang Li,
Qing He,
Lindsey Gower,
Lucy Liaw,
Robert E. Friesel

Published: March 15, 2013
https://doi.org/10.1371/journal.pone.0058746

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Marker genes
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