Somatic Mutations, Allele Loss, and DNA Methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) Gene Reveals Association with Early Age of Diagnosis in Colorectal Cancer Patients

Austin Y. Shull; Megan L. Clendenning; Sampa Ghoshal-Gupta; Christopher L. Farrell; Hima V. Vangapandu; Larry Dudas; Brent J. Wilkerson; Phillip J. Buckhaults

doi:10.1371/journal.pone.0058731

Loading metrics

Open Access

Peer-reviewed

Research Article

Somatic Mutations, Allele Loss, and DNA Methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) Gene Reveals Association with Early Age of Diagnosis in Colorectal Cancer Patients

Austin Y. Shull,

Affiliations Georgia Health Sciences University Cancer Center, Georgia Health Sciences University, Augusta, Georgia, United States of America, Department of Biochemistry and Cancer Biology, Georgia Health Sciences University, Augusta, Georgia, United States of America
⨯
Megan L. Clendenning,

Affiliation Georgia Health Sciences University Cancer Center, Georgia Health Sciences University, Augusta, Georgia, United States of America
⨯
Sampa Ghoshal-Gupta,

Affiliation Georgia Health Sciences University Cancer Center, Georgia Health Sciences University, Augusta, Georgia, United States of America
⨯
Christopher L. Farrell,

Affiliation Department of Pharmaceutical and Administrative Sciences, Presbyterian College School of Pharmacy, Clinton, South Carolina, United States of America
⨯
Hima V. Vangapandu,

Affiliation Graduate School of Biomedical Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Larry Dudas,

Affiliation Northeast Georgia Medical Center, Department of Internal Medicine, Gainesville, Georgia, United States of America
⨯
Brent J. Wilkerson,

Affiliation Department of Otolaryngology-Head and Neck Surgery, University of California Davis Medical Center, Sacramento, California, United States of America
⨯
Phillip J. Buckhaults

* E-mail: phillip.buckhaults@gmail.com

Affiliations Georgia Health Sciences University Cancer Center, Georgia Health Sciences University, Augusta, Georgia, United States of America, Department of Biochemistry and Cancer Biology, Georgia Health Sciences University, Augusta, Georgia, United States of America
⨯

Somatic Mutations, Allele Loss, and DNA Methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) Gene Reveals Association with Early Age of Diagnosis in Colorectal Cancer Patients

Austin Y. Shull,
Megan L. Clendenning,
Sampa Ghoshal-Gupta,
Christopher L. Farrell,
Hima V. Vangapandu,
Larry Dudas,
Brent J. Wilkerson,
Phillip J. Buckhaults

Published: March 7, 2013
https://doi.org/10.1371/journal.pone.0058731

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Colorectal cancer
Is the Subject Area "Colorectal cancer" applicable to this article?

Thanks for your feedback.
DNA methylation
Is the Subject Area "DNA methylation" applicable to this article?

Thanks for your feedback.
Somatic mutation
Is the Subject Area "Somatic mutation" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Methylation
Is the Subject Area "Methylation" applicable to this article?

Thanks for your feedback.
Deletion mutation
Is the Subject Area "Deletion mutation" applicable to this article?

Thanks for your feedback.
Genetic loci
Is the Subject Area "Genetic loci" applicable to this article?

Thanks for your feedback.