Rational Design of a Fibroblast Growth Factor 21-Based Clinical Candidate, LY2405319

Alexei Kharitonenkov; John M. Beals; Radmila Micanovic; Beth A. Strifler; Radhakrishnan Rathnachalam; Victor J. Wroblewski; Shun Li; Anja Koester; Amy M. Ford; Tamer Coskun; James D. Dunbar; Christine C. Cheng; Christopher C. Frye; Thomas F. Bumol; David E. Moller

doi:10.1371/journal.pone.0058575

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Open Access

Peer-reviewed

Research Article

Rational Design of a Fibroblast Growth Factor 21-Based Clinical Candidate, LY2405319

Alexei Kharitonenkov ,

* E-mail: a.kharch@lilly.com

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
John M. Beals,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Radmila Micanovic,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Beth A. Strifler,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Radhakrishnan Rathnachalam,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Victor J. Wroblewski,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Shun Li,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Anja Koester,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Amy M. Ford,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Tamer Coskun,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
James D. Dunbar,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Christine C. Cheng,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Christopher C. Frye,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Thomas F. Bumol,

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
David E. Moller

Affiliation Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯

Rational Design of a Fibroblast Growth Factor 21-Based Clinical Candidate, LY2405319

Alexei Kharitonenkov,
John M. Beals,
Radmila Micanovic,
Beth A. Strifler,
Radhakrishnan Rathnachalam,
Victor J. Wroblewski,
Shun Li,
Anja Koester,
Amy M. Ford,
Tamer Coskun

Published: March 11, 2013
https://doi.org/10.1371/journal.pone.0058575

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