Tetra- and Penta-Acylated Lipid A Structures of Porphyromonas gingivalis LPS Differentially Activate TLR4-Mediated NF-κB Signal Transduction Cascade and Immuno-Inflammatory Response in Human Gingival Fibroblasts

Open Access

Peer-reviewed

Research Article

Thanuja D. K. Herath,

Affiliation Faculty of Dentistry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
⨯
Richard P. Darveau,

Affiliation School of Dentistry, University of Washington, Seattle, Washington, United States of America
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Chaminda J. Seneviratne,

Affiliation Faculty of Dentistry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
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Cun-Yu Wang,

Affiliation School of Dentistry, University of California Los Angeles, Los Angeles, California, United States of America
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Yu Wang,

Affiliation Department of Pharmacology & Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
⨯
Lijian Jin

* E-mail: ljjin@hkucc.hku.hk

Affiliation Faculty of Dentistry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
⨯

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Lipid structure
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Transcription factors
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MAPK signaling cascades
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Signal transduction
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Cell signaling
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Cytokines
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Lipids
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Toll-like receptors
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