ON01210.Na (Ex-RAD®) Mitigates Radiation Damage through Activation of the AKT Pathway

Anthony D. Kang; Stephen C. Cosenza; Marie Bonagura; Manoj Manair; M. V. Ramana Reddy; E. Premkumar Reddy

doi:10.1371/journal.pone.0058355

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Open Access

Peer-reviewed

Research Article

ON01210.Na (Ex-RAD^®) Mitigates Radiation Damage through Activation of the AKT Pathway

Anthony D. Kang ,

Contributed equally to this work with: Anthony D. Kang, Stephen C. Cosenza

Current address: Armed Forces Radiobiology Research Institute, Bethesda, Maryland, United States of America

Affiliation Fels Institute for Cancer Research and Molecular Biology, Philadelphia, Pennsylvania, United States of America
⨯
Stephen C. Cosenza ,

Contributed equally to this work with: Anthony D. Kang, Stephen C. Cosenza

Current address: Department of Oncological Sciences, Mt. Sinai School of Medicine, New York, New York, United States of America

Affiliation Fels Institute for Cancer Research and Molecular Biology, Philadelphia, Pennsylvania, United States of America
⨯
Marie Bonagura,

Affiliation Fels Institute for Cancer Research and Molecular Biology, Philadelphia, Pennsylvania, United States of America
⨯
Manoj Manair,

Affiliation Onconova Therapeutics, Inc., Newtown, Pennsylvania, United States of America
⨯
M. V. Ramana Reddy,

Current address: Department of Oncological Sciences, Mt. Sinai School of Medicine, New York, New York, United States of America

Affiliation Fels Institute for Cancer Research and Molecular Biology, Philadelphia, Pennsylvania, United States of America
⨯
E. Premkumar Reddy

* E-mail: ep.reddy@mssm.edu

Current address: Department of Oncological Sciences, Mt. Sinai School of Medicine, New York, New York, United States of America

Affiliation Fels Institute for Cancer Research and Molecular Biology, Philadelphia, Pennsylvania, United States of America
⨯

ON01210.Na (Ex-RAD^®) Mitigates Radiation Damage through Activation of the AKT Pathway

Anthony D. Kang,
Stephen C. Cosenza,
Marie Bonagura,
Manoj Manair,
M. V. Ramana Reddy,
E. Premkumar Reddy

Published: March 7, 2013
https://doi.org/10.1371/journal.pone.0058355

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AKT signaling cascade
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