Low Density Lipoproteins Promote Unstable Calcium Handling Accompanied by Reduced SERCA2 and Connexin-40 Expression in Cardiomyocytes

Montserrat Barriga; Roi Cal; Nuria Cabello; Anna Llach; Alexander Vallmitjana; Raúl Benítez; Lina Badimon; Juan Cinca; Vicenta Llorente-Cortés; Leif Hove-Madsen

doi:10.1371/journal.pone.0058128

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Peer-reviewed

Research Article

Low Density Lipoproteins Promote Unstable Calcium Handling Accompanied by Reduced SERCA2 and Connexin-40 Expression in Cardiomyocytes

Montserrat Barriga ,

Contributed equally to this work with: Montserrat Barriga, Roi Cal

Affiliation Cardiovascular Research Center, Consejo Superior de Investigaciones Cientificas, Insitut Català de Ciencies Cardiovasculars and Institut d'Investigació Biomedica Sant Pau, Barcelona, Spain
⨯
Roi Cal ,

Contributed equally to this work with: Montserrat Barriga, Roi Cal

Affiliation Cardiovascular Research Center, Consejo Superior de Investigaciones Cientificas, Insitut Català de Ciencies Cardiovasculars and Institut d'Investigació Biomedica Sant Pau, Barcelona, Spain
⨯
Nuria Cabello,

Affiliation Cardiovascular Research Center, Consejo Superior de Investigaciones Cientificas, Insitut Català de Ciencies Cardiovasculars and Institut d'Investigació Biomedica Sant Pau, Barcelona, Spain
⨯
Anna Llach,

Affiliation Cardiology Service, Institut d'Investigació Biomedica Sant Pau and Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Alexander Vallmitjana,

Affiliation Dept. Ingeniería de Sistemas, Automática e Informática Industrial, Universitat Politècnica de Catalunya, Barcelona, Spain
⨯
Raúl Benítez,

Affiliation Dept. Ingeniería de Sistemas, Automática e Informática Industrial, Universitat Politècnica de Catalunya, Barcelona, Spain
⨯
Lina Badimon,

Affiliations Cardiovascular Research Center, Consejo Superior de Investigaciones Cientificas, Insitut Català de Ciencies Cardiovasculars and Institut d'Investigació Biomedica Sant Pau, Barcelona, Spain, Centro de Investigación Biomédica en Red de Obesidad y Nutricion, Barcelona, Spain
⨯
Juan Cinca,

Affiliation Cardiology Service, Institut d'Investigació Biomedica Sant Pau and Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Vicenta Llorente-Cortés ,

* E-mail: lhove@csic-iccc.org (LH-M); cllorente@csic-iccc.org (VL-C)

Affiliation Cardiovascular Research Center, Consejo Superior de Investigaciones Cientificas, Insitut Català de Ciencies Cardiovasculars and Institut d'Investigació Biomedica Sant Pau, Barcelona, Spain
⨯
Leif Hove-Madsen

* E-mail: lhove@csic-iccc.org (LH-M); cllorente@csic-iccc.org (VL-C)

Affiliation Cardiovascular Research Center, Consejo Superior de Investigaciones Cientificas, Insitut Català de Ciencies Cardiovasculars and Institut d'Investigació Biomedica Sant Pau, Barcelona, Spain
⨯

Low Density Lipoproteins Promote Unstable Calcium Handling Accompanied by Reduced SERCA2 and Connexin-40 Expression in Cardiomyocytes

Montserrat Barriga,
Roi Cal,
Nuria Cabello,
Anna Llach,
Alexander Vallmitjana,
Raúl Benítez,
Lina Badimon,
Juan Cinca,
Vicenta Llorente-Cortés,
Leif Hove-Madsen

Published: March 13, 2013
https://doi.org/10.1371/journal.pone.0058128

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Calcium signaling
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Cardiomyocytes
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Calcium imaging
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