EM Structure of the Ectodomain of Integrin CD11b/CD18 and Localization of Its Ligand-Binding Site Relative to the Plasma Membrane

Open Access

Peer-reviewed

Research Article

Brian D. Adair,

Affiliation Structural Biology Program, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America
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Jian-Ping Xiong,

Affiliation Structural Biology Program, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America
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José Luis Alonso,

Affiliation Leukocyte Biology and Inflammation Program, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America
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Bradley T. Hyman,

Affiliation Division of Nephrology, and Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America
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M. Amin Arnaout

* E-mail: aarnaout1@partners.org

Affiliations Structural Biology Program, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America, Leukocyte Biology and Inflammation Program, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America
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Integrins
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Crystal structure
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Cell membranes
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Electron microscopy
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Fluorescence imaging
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Protein structure
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Fluorescence resonance energy transfer
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Sequence alignment
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