A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis

Seiji Mori; Vu Tran; Kyoko Nishikawa; Teruya Kaneda; Yoshinosuke Hamada; Naomasa Kawaguchi; Masaaki Fujita; Yoko K. Takada; Nariaki Matsuura; Min Zhao; Yoshikazu Takada

doi:10.1371/journal.pone.0057927

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Open Access

Peer-reviewed

Research Article

A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis

Seiji Mori,

Affiliation Department of Molecular Pathology, Osaka University Graduate School of Medicine, Division of Health Sciences, Suita, Osaka, Japan
⨯
Vu Tran,

Affiliation Department of Dermatology, School of Medicine, University of California Davis, Sacramento, California, United States of America
⨯
Kyoko Nishikawa,

Affiliation Department of Molecular Pathology, Osaka University Graduate School of Medicine, Division of Health Sciences, Suita, Osaka, Japan
⨯
Teruya Kaneda,

Affiliation Department of Molecular Pathology, Osaka University Graduate School of Medicine, Division of Health Sciences, Suita, Osaka, Japan
⨯
Yoshinosuke Hamada,

Affiliation Department of Molecular Pathology, Osaka University Graduate School of Medicine, Division of Health Sciences, Suita, Osaka, Japan
⨯
Naomasa Kawaguchi,

Affiliation Department of Molecular Pathology, Osaka University Graduate School of Medicine, Division of Health Sciences, Suita, Osaka, Japan
⨯
Masaaki Fujita,

Affiliations Department of Dermatology, School of Medicine, University of California Davis, Sacramento, California, United States of America, Department of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, California, United States of America
⨯
Yoko K. Takada,

Affiliations Department of Dermatology, School of Medicine, University of California Davis, Sacramento, California, United States of America, Department of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, California, United States of America
⨯
Nariaki Matsuura,

Affiliation Department of Molecular Pathology, Osaka University Graduate School of Medicine, Division of Health Sciences, Suita, Osaka, Japan
⨯
Min Zhao,

Affiliation Department of Dermatology, School of Medicine, University of California Davis, Sacramento, California, United States of America
⨯
Yoshikazu Takada

* E-mail: ytakada@ucdavis.edu

Affiliations Department of Dermatology, School of Medicine, University of California Davis, Sacramento, California, United States of America, Department of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, California, United States of America
⨯

A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis

Seiji Mori,
Vu Tran,
Kyoko Nishikawa,
Teruya Kaneda,
Yoshinosuke Hamada,
Naomasa Kawaguchi,
Masaaki Fujita,
Yoko K. Takada,
Nariaki Matsuura,
Min Zhao

Published: February 28, 2013
https://doi.org/10.1371/journal.pone.0057927

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