Astrocytes Protect Neurons against Methylmercury via ATP/P2Y1 Receptor-Mediated Pathways in Astrocytes

Yusuke Noguchi; Youichi Shinozaki; Kayoko Fujishita; Keisuke Shibata; Yoshio Imura; Yosuke Morizawa; Christian Gachet; Schuichi Koizumi

doi:10.1371/journal.pone.0057898

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Open Access

Peer-reviewed

Research Article

Astrocytes Protect Neurons against Methylmercury via ATP/P2Y₁ Receptor-Mediated Pathways in Astrocytes

Yusuke Noguchi ,

Contributed equally to this work with: Yusuke Noguchi, Youichi Shinozaki, Kayoko Fujishita

Affiliation Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan
⨯
Youichi Shinozaki ,

Contributed equally to this work with: Yusuke Noguchi, Youichi Shinozaki, Kayoko Fujishita

Affiliations Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan, Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, Tokyo, Japan
⨯
Kayoko Fujishita ,

Contributed equally to this work with: Yusuke Noguchi, Youichi Shinozaki, Kayoko Fujishita

Affiliation Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan
⨯
Keisuke Shibata,

Affiliations Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan, Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, Tokyo, Japan
⨯
Yoshio Imura,

Affiliation Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan
⨯
Yosuke Morizawa,

Affiliation Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan
⨯
Christian Gachet,

Affiliation UMR_S949 INSERM, Université de Strasbourg, Etablissement Français du Sang-Alsace, Strasbourg, France
⨯
Schuichi Koizumi

* E-mail: skoizumi@yamanashi.ac.jp

Affiliations Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan, Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, Tokyo, Japan
⨯

Astrocytes Protect Neurons against Methylmercury via ATP/P2Y₁ Receptor-Mediated Pathways in Astrocytes

Yusuke Noguchi,
Youichi Shinozaki,
Kayoko Fujishita,
Keisuke Shibata,
Yoshio Imura,
Yosuke Morizawa,
Christian Gachet,
Schuichi Koizumi

Published: February 28, 2013
https://doi.org/10.1371/journal.pone.0057898

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