Differences in Gene Expression and Cytokine Release Profiles Highlight the Heterogeneity of Distinct Subsets of Adipose Tissue-Derived Stem Cells in the Subcutaneous and Visceral Adipose Tissue in Humans

Sebastio Perrini; Romina Ficarella; Ernesto Picardi; Angelo Cignarelli; Maria Barbaro; Pasquale Nigro; Alessandro Peschechera; Orazio Palumbo; Massimo Carella; Michele De Fazio; Annalisa Natalicchio; Luigi Laviola; Graziano Pesole; Francesco Giorgino

doi:10.1371/journal.pone.0057892

Loading metrics

Open Access

Peer-reviewed

Research Article

Differences in Gene Expression and Cytokine Release Profiles Highlight the Heterogeneity of Distinct Subsets of Adipose Tissue-Derived Stem Cells in the Subcutaneous and Visceral Adipose Tissue in Humans

Sebastio Perrini,

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯
Romina Ficarella,

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯
Ernesto Picardi,

Affiliation Department of Biosciences, Biotechnology and Pharmacological Sciences, University of Bari Aldo Moro, Bari, Italy
⨯
Angelo Cignarelli,

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯
Maria Barbaro,

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯
Pasquale Nigro,

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯
Alessandro Peschechera,

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯
Orazio Palumbo,

Affiliation Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
⨯
Massimo Carella,

Affiliation Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
⨯
Michele De Fazio,

Affiliation Section on General Surgery and Liver Transplantation, University of Bari Aldo Moro, Bari, Italy
⨯
Annalisa Natalicchio,

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯
Luigi Laviola,

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯
Graziano Pesole,

Affiliations Department of Biosciences, Biotechnology and Pharmacological Sciences, University of Bari Aldo Moro, Bari, Italy, Institute of Biomembranes and Bioenergetics, National Research Council, Bari, Italy
⨯
Francesco Giorgino

* E-mail: francesco.giorgino@uniba.it

Affiliation Department of Emergency and Organ Transplantation, Section on Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy
⨯

Differences in Gene Expression and Cytokine Release Profiles Highlight the Heterogeneity of Distinct Subsets of Adipose Tissue-Derived Stem Cells in the Subcutaneous and Visceral Adipose Tissue in Humans

Sebastio Perrini,
Romina Ficarella,
Ernesto Picardi,
Angelo Cignarelli,
Maria Barbaro,
Pasquale Nigro,
Alessandro Peschechera,
Orazio Palumbo,
Massimo Carella,
Michele De Fazio

Published: March 5, 2013
https://doi.org/10.1371/journal.pone.0057892

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Adipose tissue
Is the Subject Area "Adipose tissue" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Adipocytes
Is the Subject Area "Adipocytes" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Adipocyte differentiation
Is the Subject Area "Adipocyte differentiation" applicable to this article?

Thanks for your feedback.
Cell cycle and cell division
Is the Subject Area "Cell cycle and cell division" applicable to this article?

Thanks for your feedback.
Principal component analysis
Is the Subject Area "Principal component analysis" applicable to this article?

Thanks for your feedback.
Hierarchical clustering
Is the Subject Area "Hierarchical clustering" applicable to this article?

Thanks for your feedback.