Caspase-2 Is Upregulated after Sciatic Nerve Transection and Its Inhibition Protects Dorsal Root Ganglion Neurons from Apoptosis after Serum Withdrawal

Open Access

Peer-reviewed

Research Article

Vasanthy Vigneswara,

Affiliations Neurotrauma and Neurodegeneration Section, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom, Neuregenix Ltd, The Science Park, Edgbaston, Birmingham, United Kingdom
⨯
Martin Berry,

Affiliations Neurotrauma and Neurodegeneration Section, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom, Neuregenix Ltd, The Science Park, Edgbaston, Birmingham, United Kingdom
⨯
Ann Logan ,

Contributed equally to this work with: Ann Logan, Zubair Ahmed

Affiliations Neurotrauma and Neurodegeneration Section, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom, Neuregenix Ltd, The Science Park, Edgbaston, Birmingham, United Kingdom
⨯
Zubair Ahmed

Contributed equally to this work with: Ann Logan, Zubair Ahmed

* E-mail: z.ahmed.1@bham.ac.uk

Affiliations Neurotrauma and Neurodegeneration Section, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom, Neuregenix Ltd, The Science Park, Edgbaston, Birmingham, United Kingdom
⨯

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Apoptosis
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Schwann cells
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Immunohistochemistry techniques
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Small interfering RNA
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Axons
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Neuronal death
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Neuronal tuning
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Sensory perception
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