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Open Access
Peer-reviewed
Research Article
Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults
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Caroline Ogwang ,
Contributed equally to this work with: Caroline Ogwang, Muhammed Afolabi
Affiliation Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya
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Muhammed Afolabi ,
Contributed equally to this work with: Caroline Ogwang, Muhammed Afolabi
Affiliation Medical Research Council Unit, Fajara, The Gambia
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Domtila Kimani,
Affiliation Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya
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Ya Jankey Jagne,
Affiliation Medical Research Council Unit, Fajara, The Gambia
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Susanne H. Sheehy ,
* E-mail: Susanne.sheehy@ndm.ox.ac.uk
Affiliation Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, United Kingdom
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Carly M. Bliss,
Affiliation The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, United Kingdom
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Christopher J. A. Duncan,
Affiliation Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, United Kingdom
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Katharine A. Collins,
Affiliation The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, United Kingdom
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Miguel A. Garcia Knight,
Affiliation Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya
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Eva Kimani,
Affiliation Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya
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Nicholas A. Anagnostou,
Affiliation Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, United Kingdom
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Eleanor Berrie,
Affiliation Clinical Biomanufacturing Facility, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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Sarah Moyle,
Affiliation Clinical Biomanufacturing Facility, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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Sarah C. Gilbert,
Affiliation The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, United Kingdom
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Alexandra J. Spencer,
Affiliation The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, United Kingdom
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Peninah Soipei,
Affiliation Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya
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Jenny Mueller,
Affiliation Medical Research Council Unit, Fajara, The Gambia
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Joseph Okebe,
Affiliation Medical Research Council Unit, Fajara, The Gambia
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Stefano Colloca,
Affiliation Okairòs AG, Rome, Italy
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Riccardo Cortese,
Affiliations Okairòs AG, Rome, Italy, CEINGE, Naples, Italy
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Nicola K. Viebig,
Affiliation European Vaccine Initiative, Heidelberg, Germany
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Rachel Roberts,
Affiliation Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, United Kingdom
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Katherine Gantlett,
Affiliation Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, United Kingdom
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Alison M. Lawrie,
Affiliation Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, United Kingdom
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Alfredo Nicosia,
Affiliations Okairòs AG, Rome, Italy, CEINGE, Naples, Italy, Department of Molecular Medicine and Medical Biotechnology, University Federico II Naples, Naples, Italy
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Egeruan B. Imoukhuede,
Affiliation European Vaccine Initiative, Heidelberg, Germany
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Philip Bejon,
Affiliation Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya
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Britta C. Urban,
Affiliations Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
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Katie L. Flanagan,
Affiliation Medical Research Council Unit, Fajara, The Gambia
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Katie J. Ewer,
Affiliation The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, United Kingdom
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Roma Chilengi,
Affiliation Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya
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Adrian V. S. Hill,
Affiliations Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, United Kingdom, The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, United Kingdom
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Kalifa Bojang
Affiliation Medical Research Council Unit, Fajara, The Gambia
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Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults
- Caroline Ogwang,
- Muhammed Afolabi,
- Domtila Kimani,
- Ya Jankey Jagne,
- Susanne H. Sheehy,
- Carly M. Bliss,
- Christopher J. A. Duncan,
- Katharine A. Collins,
- Miguel A. Garcia Knight,
- Eva Kimani
- Published: March 19, 2013
- https://doi.org/10.1371/journal.pone.0057726