Inhibition of the NAD-Dependent Protein Deacetylase SIRT2 Induces Granulocytic Differentiation in Human Leukemia Cells

• Yoshitaka Sunami,

  Affiliation Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan

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• Marito Araki,

  Affiliation Department of Transfusion Medicine and Stem Cell Regulation, Juntendo University School of Medicine, Tokyo, Japan

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• Yumi Hironaka,

  Affiliation Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan

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• Soji Morishita,

  Affiliation Department of Transfusion Medicine and Stem Cell Regulation, Juntendo University School of Medicine, Tokyo, Japan

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• Masaki Kobayashi,

  Affiliations Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan, Central Research Laboratories, Sysmex Corporation, Hyogo, Japan

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• Ei Leen Liew,

  Affiliations Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan, Fujii Memorial Research Institute, Otsuka Pharmaceutical Co., Ltd., Shiga, Japan

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• Yoko Edahiro,

  Affiliation Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan

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• Miyuki Tsutsui,

  Affiliation Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan

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• Akimichi Ohsaka,

  Affiliation Department of Transfusion Medicine and Stem Cell Regulation, Juntendo University School of Medicine, Tokyo, Japan

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• Norio Komatsu

  * E-mail: komatsun@juntendo.ac.jp

  Affiliation Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan

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