Expression of Biliverdin Reductase A in Peripheral Blood Leukocytes Is Associated with Treatment Response in HCV-Infected Patients

Iva Subhanova; Lucie Muchova; Martin Lenicek; Hendrik J. Vreman; Ondrej Luksan; Kristyna Kubickova; Miluse Kreidlova; Tomas Zima; Libor Vitek; Petr Urbanek

doi:10.1371/journal.pone.0057555

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Open Access

Peer-reviewed

Research Article

Expression of Biliverdin Reductase A in Peripheral Blood Leukocytes Is Associated with Treatment Response in HCV-Infected Patients

Iva Subhanova ,

* E-mail: iva.subhanova@seznam.cz

Affiliation Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
⨯
Lucie Muchova,

Affiliation Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
⨯
Martin Lenicek,

Affiliation Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
⨯
Hendrik J. Vreman,

Affiliation Department of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Ondrej Luksan,

Affiliation Centre of Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
⨯
Kristyna Kubickova,

Affiliation Department of Internal Medicine, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
⨯
Miluse Kreidlova,

Affiliation Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
⨯
Tomas Zima,

Affiliation Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
⨯
Libor Vitek ,

Contributed equally to this work with: Libor Vitek, Petr Urbanek

Affiliations Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 4th Department of Internal Medicine, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
⨯
Petr Urbanek

Contributed equally to this work with: Libor Vitek, Petr Urbanek

Affiliation Department of Internal Medicine, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
⨯

Expression of Biliverdin Reductase A in Peripheral Blood Leukocytes Is Associated with Treatment Response in HCV-Infected Patients

Iva Subhanova,
Lucie Muchova,
Martin Lenicek,
Hendrik J. Vreman,
Ondrej Luksan,
Kristyna Kubickova,
Miluse Kreidlova,
Tomas Zima,
Libor Vitek,
Petr Urbanek

Published: March 11, 2013
https://doi.org/10.1371/journal.pone.0057555

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Antiviral therapy
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Hepatitis C virus
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Heme
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Blood
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Gene expression
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White blood cells
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Bilirubin
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Genetic interference
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