Corneal Endothelial Cells Provide Evidence of Accelerated Cellular Senescence Associated with HIV Infection: A Case-Control Study

Sophia Pathai; Stephen D. Lawn; Paul G. Shiels; Helen A. Weiss; Colin Cook; Robin Wood; Clare E. Gilbert

doi:10.1371/journal.pone.0057422

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Peer-reviewed

Research Article

Corneal Endothelial Cells Provide Evidence of Accelerated Cellular Senescence Associated with HIV Infection: A Case-Control Study

Sophia Pathai ,

* E-mail: Sophia.pathai@lshtm.ac.uk

Affiliations International Centre for Eye Health, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
⨯
Stephen D. Lawn,

Affiliations Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Paul G. Shiels,

Affiliation Institute of Cancer Sciences, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom
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Helen A. Weiss,

Affiliation Medical Research Council Tropical Epidemiology Group, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom
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Colin Cook,

Affiliation Department of Ophthalmology, Faculty of Health Sciences, University of Cape Town, H53 Old Main Building, Groote Schuur Hospital, Cape Town, South Africa
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Robin Wood,

Affiliation Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
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Clare E. Gilbert

Affiliation International Centre for Eye Health, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯

Corneal Endothelial Cells Provide Evidence of Accelerated Cellular Senescence Associated with HIV Infection: A Case-Control Study

Sophia Pathai,
Stephen D. Lawn,
Paul G. Shiels,
Helen A. Weiss,
Colin Cook,
Robin Wood,
Clare E. Gilbert

Published: February 27, 2013
https://doi.org/10.1371/journal.pone.0057422

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Cornea
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Senescence
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