Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting

Tiewei Cheng; Beat Roth; Woonyoung Choi; Peter C. Black; Colin Dinney; David J. McConkey

doi:10.1371/journal.pone.0057284

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Peer-reviewed

Research Article

Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting

Tiewei Cheng,

Affiliations Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Experimental Therapeutics Academic Program, The University of Texas-Graduate School of Biomedical Sciences (GSBS) at Houston, Houston, Texas, United States of America
⨯
Beat Roth,

Affiliation Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Woonyoung Choi,

Affiliations Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Peter C. Black,

Affiliation Department of Urologic Science, The University of British Columbia, Vancouver, British Columbia, Canada
⨯
Colin Dinney,

Affiliations Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
David J. McConkey

* E-mail: dmcconke@mdanderson.org

Affiliations Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Experimental Therapeutics Academic Program, The University of Texas-Graduate School of Biomedical Sciences (GSBS) at Houston, Houston, Texas, United States of America
⨯

Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting

Tiewei Cheng,
Beat Roth,
Woonyoung Choi,
Peter C. Black,
Colin Dinney,
David J. McConkey

Published: February 26, 2013
https://doi.org/10.1371/journal.pone.0057284

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Metastasis
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Fibroblast growth factor
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Gene expression
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Bladder cancer
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