A Small Molecule (Pluripotin) as a Tool for Studying Cancer Stem Cell Biology: Proof of Concept

Susan D. Mertins; Dominic A. Scudiero; Melinda G. Hollingshead; Raymond D. Divelbiss Jr; Michael C. Alley; Anne Monks; David G. Covell; Karen M. Hite; David S. Salomon; John E. Niederhuber

doi:10.1371/journal.pone.0057099

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Open Access

Peer-reviewed

Research Article

A Small Molecule (Pluripotin) as a Tool for Studying Cancer Stem Cell Biology: Proof of Concept

Susan D. Mertins ,

* E-mail: smertins@mail.nih.gov

Affiliation Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
⨯
Dominic A. Scudiero,

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
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Melinda G. Hollingshead,

Affiliation Biological Testing Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
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Raymond D. Divelbiss Jr,

Affiliation Biological Testing Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
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Michael C. Alley,

Affiliation Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
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Anne Monks,

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
⨯
David G. Covell,

Affiliation Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
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Karen M. Hite,

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
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David S. Salomon,

Affiliation Mammary Biology and Tumorigenesis Laboratory, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America
⨯
John E. Niederhuber

Affiliation Cell and Cancer Biology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America
⨯

A Small Molecule (Pluripotin) as a Tool for Studying Cancer Stem Cell Biology: Proof of Concept

Susan D. Mertins,
Dominic A. Scudiero,
Melinda G. Hollingshead,
Raymond D. Divelbiss Jr,
Michael C. Alley,
Anne Monks,
David G. Covell,
Karen M. Hite,
David S. Salomon,
John E. Niederhuber

Published: February 21, 2013
https://doi.org/10.1371/journal.pone.0057099

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