Phagocytosis Is the Main CR3-Mediated Function Affected by the Lupus-Associated Variant of CD11b in Human Myeloid Cells

Liliane Fossati-Jimack; Guang Sheng Ling; Andrea Cortini; Marta Szajna; Talat H. Malik; Jacqueline U. McDonald; Matthew C. Pickering; H. Terence Cook; Philip R. Taylor; Marina Botto

doi:10.1371/journal.pone.0057082

Loading metrics

Open Access

Peer-reviewed

Research Article

Phagocytosis Is the Main CR3-Mediated Function Affected by the Lupus-Associated Variant of CD11b in Human Myeloid Cells

Liliane Fossati-Jimack ,

Contributed equally to this work with: Liliane Fossati-Jimack, Guang Sheng Ling

Affiliation Centre for Complement and Inflammation Research, Division of Immunology and Inflammation, Department of Medicine, Imperial College, London, United Kingdom
⨯
Guang Sheng Ling ,

Contributed equally to this work with: Liliane Fossati-Jimack, Guang Sheng Ling

Affiliation Centre for Complement and Inflammation Research, Division of Immunology and Inflammation, Department of Medicine, Imperial College, London, United Kingdom
⨯
Andrea Cortini,

Affiliation Centre for Complement and Inflammation Research, Division of Immunology and Inflammation, Department of Medicine, Imperial College, London, United Kingdom
⨯
Marta Szajna,

Affiliation Centre for Complement and Inflammation Research, Division of Immunology and Inflammation, Department of Medicine, Imperial College, London, United Kingdom
⨯
Talat H. Malik,

Affiliation Centre for Complement and Inflammation Research, Division of Immunology and Inflammation, Department of Medicine, Imperial College, London, United Kingdom
⨯
Jacqueline U. McDonald,

Affiliation Cardiff Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom
⨯
Matthew C. Pickering,

Affiliation Centre for Complement and Inflammation Research, Division of Immunology and Inflammation, Department of Medicine, Imperial College, London, United Kingdom
⨯
H. Terence Cook,

Affiliation Centre for Complement and Inflammation Research, Division of Immunology and Inflammation, Department of Medicine, Imperial College, London, United Kingdom
⨯
Philip R. Taylor,

Affiliation Cardiff Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom
⨯
Marina Botto

* E-mail: m.botto@imperial.ac.uk

Affiliation Centre for Complement and Inflammation Research, Division of Immunology and Inflammation, Department of Medicine, Imperial College, London, United Kingdom
⨯

Phagocytosis Is the Main CR3-Mediated Function Affected by the Lupus-Associated Variant of CD11b in Human Myeloid Cells

Liliane Fossati-Jimack,
Guang Sheng Ling,
Andrea Cortini,
Marta Szajna,
Talat H. Malik,
Jacqueline U. McDonald,
Matthew C. Pickering,
H. Terence Cook,
Philip R. Taylor,
Marina Botto

Published: February 22, 2013
https://doi.org/10.1371/journal.pone.0057082

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Phagocytosis
Is the Subject Area "Phagocytosis" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
Monocytes
Is the Subject Area "Monocytes" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Alleles
Is the Subject Area "Alleles" applicable to this article?

Thanks for your feedback.
Systemic lupus erythematosus
Is the Subject Area "Systemic lupus erythematosus" applicable to this article?

Thanks for your feedback.