Electrical Vagus Nerve Stimulation Attenuates Systemic Inflammation and Improves Survival in a Rat Heatstroke Model

Kazuma Yamakawa; Naoya Matsumoto; Yukio Imamura; Takashi Muroya; Tomoki Yamada; Junichiro Nakagawa; Junya Shimazaki; Hiroshi Ogura; Yasuyuki Kuwagata; Takeshi Shimazu

doi:10.1371/journal.pone.0056728

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Open Access

Peer-reviewed

Research Article

Electrical Vagus Nerve Stimulation Attenuates Systemic Inflammation and Improves Survival in a Rat Heatstroke Model

Kazuma Yamakawa ,

* E-mail: k.yamakawa0911@gmail.com

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Naoya Matsumoto,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Yukio Imamura,

Affiliation Unit for Liveable Cities, Human Health Science, Kyoto University Graduate School of Medicine, Kyoto, Japan
⨯
Takashi Muroya,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Tomoki Yamada,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Junichiro Nakagawa,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Junya Shimazaki,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Hiroshi Ogura,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Yasuyuki Kuwagata,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Takeshi Shimazu

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯

Electrical Vagus Nerve Stimulation Attenuates Systemic Inflammation and Improves Survival in a Rat Heatstroke Model

Kazuma Yamakawa,
Naoya Matsumoto,
Yukio Imamura,
Takashi Muroya,
Tomoki Yamada,
Junichiro Nakagawa,
Junya Shimazaki,
Hiroshi Ogura,
Yasuyuki Kuwagata,
Takeshi Shimazu

Published: February 12, 2013
https://doi.org/10.1371/journal.pone.0056728

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Functional electrical stimulation
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