Label-Free Detection of Neuronal Differentiation in Cell Populations Using High-Throughput Live-Cell Imaging of PC12 Cells

Sebastian Weber; María L. Fernández-Cachón; Juliana M. Nascimento; Steffen Knauer; Barbara Offermann; Robert F. Murphy; Melanie Boerries; Hauke Busch

doi:10.1371/journal.pone.0056690

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Peer-reviewed

Research Article

Label-Free Detection of Neuronal Differentiation in Cell Populations Using High-Throughput Live-Cell Imaging of PC12 Cells

Sebastian Weber ,

Contributed equally to this work with: Sebastian Weber, María L. Fernández-Cachón, Melanie Boerries, Hauke Busch

Affiliations Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-University Freiburg, Freiburg, Germany, Center for Biological Systems Analysis, Albert-Ludwigs-University Freiburg, Freiburg, Germany
⨯
María L. Fernández-Cachón ,

Contributed equally to this work with: Sebastian Weber, María L. Fernández-Cachón, Melanie Boerries, Hauke Busch

Affiliations Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-University Freiburg, Freiburg, Germany, Center for Biological Systems Analysis, Albert-Ludwigs-University Freiburg, Freiburg, Germany
⨯
Juliana M. Nascimento,

Affiliations Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-University Freiburg, Freiburg, Germany, Center for Biological Systems Analysis, Albert-Ludwigs-University Freiburg, Freiburg, Germany
⨯
Steffen Knauer,

Affiliations Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-University Freiburg, Freiburg, Germany, Center for Biological Systems Analysis, Albert-Ludwigs-University Freiburg, Freiburg, Germany
⨯
Barbara Offermann,

Affiliation Center for Biological Systems Analysis, Albert-Ludwigs-University Freiburg, Freiburg, Germany
⨯
Robert F. Murphy,

Affiliations Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-University Freiburg, Freiburg, Germany, Center for Biological Systems Analysis, Albert-Ludwigs-University Freiburg, Freiburg, Germany, Lane Center for Computational Biology and Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
⨯
Melanie Boerries ,

Contributed equally to this work with: Sebastian Weber, María L. Fernández-Cachón, Melanie Boerries, Hauke Busch

* E-mail: melanie.boerries@frias.uni-freiburg.de (MB); hauke.busch@frias.uni-freiburg.de (HB)

Affiliations Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-University Freiburg, Freiburg, Germany, Center for Biological Systems Analysis, Albert-Ludwigs-University Freiburg, Freiburg, Germany
⨯
Hauke Busch

Contributed equally to this work with: Sebastian Weber, María L. Fernández-Cachón, Melanie Boerries, Hauke Busch

* E-mail: melanie.boerries@frias.uni-freiburg.de (MB); hauke.busch@frias.uni-freiburg.de (HB)

Affiliations Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-University Freiburg, Freiburg, Germany, Center for Biological Systems Analysis, Albert-Ludwigs-University Freiburg, Freiburg, Germany
⨯

Label-Free Detection of Neuronal Differentiation in Cell Populations Using High-Throughput Live-Cell Imaging of PC12 Cells

Sebastian Weber,
María L. Fernández-Cachón,
Juliana M. Nascimento,
Steffen Knauer,
Barbara Offermann,
Robert F. Murphy,
Melanie Boerries,
Hauke Busch

Published: February 22, 2013
https://doi.org/10.1371/journal.pone.0056690

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