Compensatory Effort Parallels Midbrain Deactivation during Mental Fatigue: An fMRI Study

• Seishu Nakagawa ,

  * E-mail: seishu@idac.tohoku.ac.jp

  Affiliation Department of Functional Brain Imaging, Institute of Development, Aging and Cancer, (IDAC), Tohoku University, Sendai, Japan

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• Motoaki Sugiura,

  Affiliations Department of Functional Brain Imaging, Institute of Development, Aging and Cancer, (IDAC), Tohoku University, Sendai, Japan, International Research Institute of Disaster Science, Tohoku University, Sendai, Japan

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• Yuko Akitsuki,

  Affiliation Smart Ageing Center, IDAC, Tohoku University, Sendai, Japan

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• S. M. Hadi Hosseini,

  Affiliations Department of Functional Brain Imaging, Institute of Development, Aging and Cancer, (IDAC), Tohoku University, Sendai, Japan, Department of Psychiatry and Behavioral Sciences, Stanford, Center for Interdisciplinary Brain Sciences Research, School of Medicine, Stanford University, Stanford, California, United States of America

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• Yuka Kotozaki,

  Affiliation Smart Ageing Center, IDAC, Tohoku University, Sendai, Japan

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• Carlos Makoto Miyauchi,

  Affiliation Department of Functional Brain Imaging, Institute of Development, Aging and Cancer, (IDAC), Tohoku University, Sendai, Japan

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• Yukihito Yomogida,

  Affiliations Department of Functional Brain Imaging, Institute of Development, Aging and Cancer, (IDAC), Tohoku University, Sendai, Japan, Japan Society for the Promotion of Science, Tokyo, Japan

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• Ryoichi Yokoyama,

  Affiliation Department of Functional Brain Imaging, Institute of Development, Aging and Cancer, (IDAC), Tohoku University, Sendai, Japan

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• Hikaru Takeuchi,

  Affiliation Smart Ageing Center, IDAC, Tohoku University, Sendai, Japan

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• Ryuta Kawashima

  Affiliations Department of Functional Brain Imaging, Institute of Development, Aging and Cancer, (IDAC), Tohoku University, Sendai, Japan, Smart Ageing Center, IDAC, Tohoku University, Sendai, Japan

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